Surgical management of secondary hyperparathyroidism ; 32. Bone disease in renal transplant recipients; 30. Clinical consequences of arterial calcifications and soft-tissue calcifications in Chronic Kidney Disease; 19. The Spectrum of Mineral and Bone Disorder in Chronic Kidney Disease Klaus Olgaard, Justin Silver, Isidro B. Professor Silver has published more than 160 papers and reviews on this and related fields, including fifteen book chapters. Imaging and intervention of parathyroid hyperplasia ; 31. Together with his colleague Tally Naveh-Many Ph.
Phosphatonins in health and disease 24. Considerably more problematic is the use of calcilytics in low turnover forms of renal osteodystrophy. In this Review, we describe our current knowledge of the factors involved in the passive and active regulation of extraosseous calcification processes, with an assessment of their importance as targets for future diagnostic and therapeutic interventions. New vitamin D analogs for chronic kidney disease patients ; 26. He is Past President of several national nephrology and transplantation societies including the Danish Society of Nephrology. He is Director of the Minerva Center for Calcium and Bone Metabolism at Hadassah Hospital. However more is now understood about the hormonal influence on bone and vascular structures, and there have been major advances in the field of bone and mineral metabolism.
You can change your cookie settings at any time. Series Title: Other Titles: Spectrum of renal osteodystrophy. However, in this 1-year study, mortality was not an end point. In 'Bedside to Bench', Sundeep Khosla discusses how this clinical study underpins research showing that mediators of inflammation and oxidative stress share common mechanisms that may lead to this calcium shift during aging. Regulation of parathyroid hormone biosynthesis and gene expression ; 6. Imaging and intervention of parathyroid hyperplasia ; 31. He is subject editor for Nephrology Dialysis Transplantation, and has been a member of several editorial boards.
Vous recevrez un lien direct pour télécharger notre appli gratuite Reader. Please or to access full text content. They have characterized the spectrum of renal osteodystrophy in paediatric patients as well as the effects of therapy with different vitamin D sterols. Responsibility: edited by Klaus Olgaard, Isidro B. The E-mail message field is required.
Pathogenesis of vascular calcification: experimental studies ; 18. Université Paris Descartes, Faculté de Médecine, Paris. Osteopenia in uremia ; 15. The use of the parent vitamin D, calcitriol, or its analogues, a variety of oral phosphorus binders and calcimimetics acting directly on the parathyroid CaR, has provided with a sense of security and wisdom indicating that we have something to offer the patients, who are persuaded to accept our advice and adhere to treatment. Calcimimetics and calcilytics in the treatment of chronic kidney disease-mineral and bone disorder ; 27. Surgical management of secondary hyperparathyroidism ; 32.
Non-invasive assessment of vascular calcification and arterial stiffness ; 14. Physiology and pathology of calcium and magnesium transport ; 23. New vitamin D analogs for chronic kidney disease patients; 26. Clinical management of vascular and soft tissue calcifications in Chronic Kidney Disease patients; 20. Description: xxvi, 590 pages : illustrations some color ; 24 cm.
All subjects received calcium-based phosphate binders. There was no change in C-reactive protein during the study period. This effect might be indirect due to lowering of serum calcium and phosphate levels and ameliorating high bone turnover or directly via CaR in the vascular walls. Acidosis and renal bone disease ; 16. The spectrum of renal osteodystrophy and vascular calcifications in uremia ; 12. Public users are able to search the site and view the abstracts for each book and chapter without a subscription. Etelcalcetide, a novel peptide agonist of the calcium-sensing receptor, prevents vascular calcification in a rat model of renal insufficiency with secondary hyperparathyroidism.
In the past 10 years, a wealth of experimental and clinical information has been published on the key pathophysiological events that contribute to the development and progression of vascular and soft-tissue calcifications. Imaging and intervention of parathyroid hyperplasia; 31. New aspects of normal bone biology; 3. Fortunately, the pharmacology of the calcium receptor and G protein-coupled receptors in general, allows signaling-specific, activating ligands. He is Past President of several national nephrology and transplantation societies including the Danish Society of Nephrology. Pathogenesis of vascular calcification: experimental studies 18.
In hemodialysis patients with moderate to severe secondary hyperparathyroidism, cinacalcet plus low-dose vitamin D sterols may attenuate vascular and cardiac valve calcification. Mechanisms for the development of congestive heart failure in type 4 cattle include pressure overload arterial hypertension and volume anemia, edematous syndrome , which increase in proportion to the decrease in renal function. . He studies the molecular biology of the parathyroid and in particular the pathophysiology of the secondary hyperparathyroidism of chronic renal failure. Was it anyway worth the effort? Marchais, Service d'Hémodialyse, Hôpital F. Clinical consequences of arterial calcifications and soft-tissue calcifications in Chronic Kidney Disease ; 19.